Analisis Drug Related Problems (DRPs) pada Pasien Acute Coronary Syndrome Di RSUD Abdul Wahab Sjahranie Samarinda
DOI:
https://doi.org/10.25026/mpc.v8i1.322Abstract
Pemakaian obat yang cukup banyak atau disebut polifarmasi pada pasien acute coronary syndrome dapat menyebabkan terjadinya Drug Related Problems (DRPs). Analisis DRPs perlu dilakukan untuk mengoptimalkan terapi yang diberikan. Tujuan penelitian yaitu untuk mengetahui karakteristik dan jumlah kejadian DRPs pada pasien acute coronary syndrome. Penelitian ini menggunakan rancangan penelitian observasional. Data diambil secara prospektif dengan mencatat rekam medik pasien dan dianalisis secara deskriptif. Kriteria inklusi adalah pasien acute coronary syndrome, dewasa, dan rawat inap di RSUD Abdul Wahab Sjahranie Samarinda dalam rentang periode Agustus-Oktober 2018. Hasil penelitian menunjukkan analisis DRP’s yang ditemukan yaitu indikasi tanpa obat (13,33%), overdose (3,33%), adverse drug reaction (20%) dan drug interactions (80%).
References
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[2] Departemen Kesehatan RI. 2007. Pharmaceutical care untuk pasien penyakit jantung koroner: focus sindrom koroner akut. Jakarta: Direktorat Bina Farmasi Komunitas dan Klinik,Ditjen Bina Kefarmasian dan Alat kesehatan Dep.Kes RI.
[3] Cipolle, R.J. 2004. Drug Therapy Problem: In Pharmaceutical Care Practie The Clinician's Guide second edition. New York: The McGraw-Hill Companies.
[4] Abraham, R.R. 2013. Drug Related Problems and Reactive Pharmacist Interventions for Inpatients Receiving Cardiovascular Drug. International Journal of Basic Medical Sciences and Pharmacy (IJBMSP).
[5] Antman, E.M. 2001.Acute Myocardial Infarction. In Braunwald Heart Disease: A Textbook of Cardiovascular Medicine, 6th ed. Wb Saunders Co.
[6] Potter. 2005. Fundamental Keperawatan Konsep, Proses dan Praktik. Jakarta: ECG.
[7] Cipto, S. 2013. Hubungan Luas Infark Miokard (berdasarkan skor selvester) dengan respon nyeri dada pada pasien syndrome coroner akut (SKA) di RSD Dr. Soebandi Jember. Jurnal Ilmu Keperawatan. Vol 1 No 2.
[8] Astutik, Widi., Didik, H., Nailis, S. 2013. Penggunaan Obat Golongan Diuretik pada Pasien Stroke Iskemik di Instalasi Rawat Inap Rsu Dr. Saiful Anwar Malang. Media Farmasi.
[9] Susilowati. 2008. Pengukuran Status Gizi Dengan Antropometri Gizi. Jakarta: CV. Trans Info Media.
[10] Aberg, J.A. 2009. Drug Information Handbook, 17th edition. American: Lexi-Comp.
[11] Perhimpunan Dokter Spesialis Kardiovaskular Indonesia (PERKI). 2015. Pedoman Tatalaksana Gagal Jantung (edisi pertama). Jakarta: PERKI.
[12] Priyanto. 2009. Farmakoterapi dan Terminologi Medis. Depok: Leskonfi.
[13] Ema, P.Y. 2018. Hubungan antara Obesitas, Konsumsi Tinggi Purin, dan Pengobatan terhadap Kadar Asam Urat dengan Penggunaan Allopurinol pada Pasien Hiperurisemia. Jurnal Farmasi Klinik Indonesia. Vol.7 No. 1. ISSN: 2252–6218
[14] Well, dkk. 2000. Pharmacotherapy handbook 2ndEd. Appleton and lange. Connecticut.
[15] Briet, M. 2010. Aldosterone: effects on the kidnay and cardiovascular system. Nat rev nephron.
[16] Yesia,SM. 2017. Kajian Potensi Interaksi Obat Antihipertensi Pada Pasien Hipertensi Primer Di Instalasi Rawat Jalan Rsud Luwuk Periode Januari – Maret 2016. Pharmacon Jurnal Ilmiah Farmasi. UNSRAT Vol. 6 No. 3
[17] Drug Interaction Checker. 2018 In : www.drug.com/druginteraction.html
[18] Yusuf, S. 2006. Comparison of Fondaparinux and Enoxaparin in Acute Coronary Syndromes.The New England Journal of Medicine..
[19] Nishio. 2005. Interaction between Amlodipine and Simvastatin in Patients with Hypercholesterolemia and Hypertension. Japan: Department of Clinical Pharmacology and Therapeutics and Department of Internal Medicine III, Hamamatsu University School of Medicine, Hamamatsu. Pharmacists Association
[20] Stockley, I.H. 2008. Stockley’s Drug Interaction. Eighth Edition. London: Pharmaceutical Press.
[21] Mallet, L, dkk. 2007. The Challenge of Managing Drug Interactions in Elderly People. Lancet.
[22] Kafeel, H. 2014, Possibility of Drug-Drug Interaction in Prescription Dispensed by Community and Hospital Pharmacy. Pharmacology and Pharmacy.
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Published
2018-12-31
How to Cite
Aditamasari, D. A., Arifian, H., & Ramadhan, A. M. (2018). Analisis Drug Related Problems (DRPs) pada Pasien Acute Coronary Syndrome Di RSUD Abdul Wahab Sjahranie Samarinda. Proceeding of Mulawarman Pharmaceuticals Conferences, 8(1), 184–190. https://doi.org/10.25026/mpc.v8i1.322
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