Sintesis 2’-Hidroksi-5’-Kloro-3,5-Dimetoksi-4-Hidroksikalkon

  • Amanuddin Amanuddin Laboratorium Penelitian dan Pengembangan Kefarmasian "Farmaka Tropis", Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia
  • Hanggara Arifian
  • Agung Rahmadani Laboratorium Penelitian dan Pengembangan Kefarmasian "Farmaka Tropis", Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia
  • Rolan Rusli Laboratorium Penelitian dan Pengembangan Kefarmasian "Farmaka Tropis", Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia http://orcid.org/0000-0003-1264-5933

Abstract

Chalcone are compounds that have 2 aromatic rings connected by 3 carbon atoms which are an α, β unsaturated carbonyl system that have various biological activities. 2'-hydroxy-5'-chloro-3,5-dimethoxy-4-hydroxicalcone was synthesized from 2'-hydroxy-5'-chloro acetophenone and syringaldehyde using a NaOH catalyst. This compound was purified using Column Chromatography by isocratic method using n-hexane:ethyl acetate (15:1) as eluent. This compound has a Rf 0.75 and 2.7% of yield.

References

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Published
2020-08-15
How to Cite
Amanuddin, A., Arifian, H., Rahmadani, A., & Rusli, R. (2020). Sintesis 2’-Hidroksi-5’-Kloro-3,5-Dimetoksi-4-Hidroksikalkon. Proceeding of Mulawarman Pharmaceuticals Conferences, 11(1), 50-53. https://doi.org/10.25026/mpc.v11i1.393

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