Formulasi Sediaan Krim Anti Aging Berbahan Aktif Ekstrak Buah Libo (Ficus variegata, Blume)
DOI:
https://doi.org/10.25026/mpc.v8i1.337Abstract
Buah libo (F.variegata) merupakan bahan alam yang berpotensi untuk melindungi kulit karena kandungan antioksidan yang terdapat didalamnya. Pengembangan bentuk sediaan dalam bentuk krim anti aging diperlukan agar dapat dimanfaatkan oleh masyarakat. Penelitian ini bertujuan untuk mengetahui formula dan konsentrasi ekstrak buah libo yang dapat memberikan efek anti aging yang baik. Penentuan efek anti aging dilakukan secara in vitro menggunakan spektrofotometer UV-VIS. Hasil uji menunjukkan bahwa krim dengan konsentrasi ekstrak 5% dan 15% memiliki aktivitas anti aging, berturut-turut adalah sebesar 73% dan 47%.
References
1 Bal S, Ding Z, Elly V, Jiskoot W, Bouwstra J. Advances in transcutaneous vaccine delivery: Do all always lead to Rome? JCR 2010;148:266–82.
2 Fox L, Gerber M, Plessis J, Hamman J. Transderma drug delivery enhancement by compounds of natural origin. Molecules 2011;16:10507–40.
3 Basler, K., Bergmann, S., Heisig, M., Naegel, A., Zom-Kruppa, M and Brandner, J.M., The role of tight junction in skin barrier function and dermal absorption. JCR 2016;242:105-18.
4 Lephart, E.D. Skin aging and oxidative stress: Equol’s anti-aging effects via biochemichal and molecular mechanisms. Ageing Research Reviews 2016:31: 36-54.
5 McDaniel DH, Nuadecker BA, DiNardo JC, Lewis JA, Maibach HI. Clinical efficacy assessment in photodamaged skin of 0,5% and 1,0% Indeboneno. JCD 2005;4:167-73.
6 Amrillah, M. S., Rusli, R., Fadraersada, J., 2015. Aktivitas Tabir Surya daun Miana (Coleus atropurpureus L. Benth). Jurnal Sains dan Kesehatan. 1 (4). 168-174. DOI: https://doi.org/10.25026/jsk.v1i4.35
7 Rusli, R., Hardina, M. P., Muflihah, F., Rahmadani, A., 2015. Profil Kromatografi Senyawa Aktif Antioksidan dan Antibakteri Fraksi n-Heksana Dan Libo (Ficus variegata Blume.) Journal Tropical Pharmaceutical Chemistry. 3 (2). 124-130. DOI: https://doi.org/10.25026/jtpc.v3i2.98
8 Rijai, L. 2013. Potensi Tumbuhan Libo (Ficus variegata Blume) Sebagai Sumber Bahan Farmasi Potensial. Journal Tropical Pharmaceutical Chemistry. 2. (3). 166-179. DOI: https://doi.org/10.25026/jtpc.v2i3.63
9 Ningsih, B. A., Rahmadani, A., Fadraersada, J., & Rusli, R. (2016). AKTIVITAS ANTIBAKTERI DAN ANTIOKSIDAN ISOLAT FRAKSI ETIL ASETAT BUAH LIBO (Ficus variegata Blume.). Proceeding of Mulawarman Pharmaceuticals Conferences, 3(2), 114-120. https://doi.org/10.25026/mpc.v3i2.95
10 R Rusli, BA Ningsih, A Rahmadani, L Febrina, V Maulidya, J Fadraersada. Isolation and Antioxidant and Antibacterial Activity of Flavonoid from Ficus variegate Blume. Indonesian Journal of Chemistry (Accepted)
11 Bernatoniene, J., Masteikova, R., 2. Davalgiene, J., Peciura, R., Gauryliene, R., Bernatoniene, R. (2011). Topical Apllication Of Calendula officinalis (L.) ; Formulation and Evaluation of Hydrophilic With Antioxidant Activity. Journal of Medicinal Plants Research, 5(6), 868-877
12 Sharon, Nela. Anam, Syariful. Yuliet. 2013. Formulasi Krim Antioksidan Ekstrak Etanol Bawang Hutan (Eleutherine palmifolia L. Merr). Online Jurnal of Natural Science,Vol 2 (3) :111-122
2 Fox L, Gerber M, Plessis J, Hamman J. Transderma drug delivery enhancement by compounds of natural origin. Molecules 2011;16:10507–40.
3 Basler, K., Bergmann, S., Heisig, M., Naegel, A., Zom-Kruppa, M and Brandner, J.M., The role of tight junction in skin barrier function and dermal absorption. JCR 2016;242:105-18.
4 Lephart, E.D. Skin aging and oxidative stress: Equol’s anti-aging effects via biochemichal and molecular mechanisms. Ageing Research Reviews 2016:31: 36-54.
5 McDaniel DH, Nuadecker BA, DiNardo JC, Lewis JA, Maibach HI. Clinical efficacy assessment in photodamaged skin of 0,5% and 1,0% Indeboneno. JCD 2005;4:167-73.
6 Amrillah, M. S., Rusli, R., Fadraersada, J., 2015. Aktivitas Tabir Surya daun Miana (Coleus atropurpureus L. Benth). Jurnal Sains dan Kesehatan. 1 (4). 168-174. DOI: https://doi.org/10.25026/jsk.v1i4.35
7 Rusli, R., Hardina, M. P., Muflihah, F., Rahmadani, A., 2015. Profil Kromatografi Senyawa Aktif Antioksidan dan Antibakteri Fraksi n-Heksana Dan Libo (Ficus variegata Blume.) Journal Tropical Pharmaceutical Chemistry. 3 (2). 124-130. DOI: https://doi.org/10.25026/jtpc.v3i2.98
8 Rijai, L. 2013. Potensi Tumbuhan Libo (Ficus variegata Blume) Sebagai Sumber Bahan Farmasi Potensial. Journal Tropical Pharmaceutical Chemistry. 2. (3). 166-179. DOI: https://doi.org/10.25026/jtpc.v2i3.63
9 Ningsih, B. A., Rahmadani, A., Fadraersada, J., & Rusli, R. (2016). AKTIVITAS ANTIBAKTERI DAN ANTIOKSIDAN ISOLAT FRAKSI ETIL ASETAT BUAH LIBO (Ficus variegata Blume.). Proceeding of Mulawarman Pharmaceuticals Conferences, 3(2), 114-120. https://doi.org/10.25026/mpc.v3i2.95
10 R Rusli, BA Ningsih, A Rahmadani, L Febrina, V Maulidya, J Fadraersada. Isolation and Antioxidant and Antibacterial Activity of Flavonoid from Ficus variegate Blume. Indonesian Journal of Chemistry (Accepted)
11 Bernatoniene, J., Masteikova, R., 2. Davalgiene, J., Peciura, R., Gauryliene, R., Bernatoniene, R. (2011). Topical Apllication Of Calendula officinalis (L.) ; Formulation and Evaluation of Hydrophilic With Antioxidant Activity. Journal of Medicinal Plants Research, 5(6), 868-877
12 Sharon, Nela. Anam, Syariful. Yuliet. 2013. Formulasi Krim Antioksidan Ekstrak Etanol Bawang Hutan (Eleutherine palmifolia L. Merr). Online Jurnal of Natural Science,Vol 2 (3) :111-122
Downloads
Published
2018-12-31
How to Cite
Amin, N. Y. A., Naspiah, N., & Rusli, R. (2018). Formulasi Sediaan Krim Anti Aging Berbahan Aktif Ekstrak Buah Libo (Ficus variegata, Blume). Proceeding of Mulawarman Pharmaceuticals Conferences, 8(1), 301–307. https://doi.org/10.25026/mpc.v8i1.337
Issue
Section
Articles
