Uji Fitokimia Ekstrak Kulit Buah Salak (Salacca zalacca) dan Pengaruh Ekstrak terhadap Pertumbuhan Bakteri Streptococcus mutans dan Jamur Candida albicans

  • Emma Susilowati S Laboratorium Penelitian dan Pengembangan Kefarmasian “Farmaka Tropis”, Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia
  • Agung Rahmadani Laboratorium Penelitian dan Pengembangan Kefarmasian “Farmaka Tropis”, Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia
  • Lisna Meylina Laboratorium Penelitian dan Pengembangan Kefarmasian “Farmaka Tropis”, Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia
  • Hadi Kuncoro Laboratorium Penelitian dan Pengembangan Kefarmasian “Farmaka Tropis”, Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia
Keywords: Snakefruit pericarp (Salacca zalacca), Metabolite Secondary, Antimicrobial, Well Method

Abstract

Snakefruit (Salacca zalacca) is one of Indonesian native plant that the pericarp of snakefruit can be used because it has activity as an antimicrobial. This study aims to identify the metabolite content of snakefruit pericarp and to investigate the potential of snakefruit pericarp extracts in inhibiting the growth of Streptococcus mutans and Candida albicans. Snakefruit pericarp was extracted by reflux method using ethanol 96%, and an extract was tested by phytochemical qualitatively and antimicrobial activity of extract was carried out using the well method, by using concentrations are 5, 10, 15, and 20%. The results showed that the extracts contains secondary metabolites i.e. alkaloids, flavonoids, saponins and tannins. Extract of snakefruit pericarp can inhibit the growth of Streptococcus mutans and Candida albicans at 5% concentration and the inhibiting activity increased together with higher concentrations of extract.

References

Volk, W.A., Wheeler, M.F. 1990. Mikrobiologi Dasar Edisi V Jilid 2. Penerbit Erlangga. Jakarta.

Dalimartha, S. 2009. Atlas Tumbuhan Obat Indonesia Jilid I. Trubus Agriwidia. Jakarta.

Rahmah, Umi. 2016. Pengaruh Ekstrak Kulit Buah Salak (Salacca zalacca (Gaertn.) Voss) Terhadap Pertumbuhan Escherichia coli. Artikel Ilmiah. Fakultas Keguruan dan Ilmu Pengetahuan Universitas Jambi.

Laffiani, Yunita. 2017. Efektivitas Ekstrak Kulit Salak Pondoh (Salacca zalacca) terhadap Pertumbuhan Candida albicans pada Plat Resin Akrilik. Karya Tulis Ilmiah. UMY Yogyakarta.

Simaremare, Eva Susanty. 2014. Skrining Fitokimia Etanol Daun Gatal (Laportea decumana (Roxb.) Wedd). Pharmacy. Volume 1 (01). ISSN 1693-3591.

Illing, Ilmiat., Wulan Safitri dan Erfiana. 2017. Uji Fitokimia Ekstrak Buah Dengen. Jurnal Dinamika. Volume 08 (01). E-ISSN 2503-4863.

Alasa, Astrid natalia., Syariful Anam dan Jamaluddin. 2017. Analisis Kadar Total Metabolit Sekunder Ekstrak Etanol Daun Tamoenju (Hibiscus surattensis L.). Kovalen. Volume 3 (3). E-ISSN 2477-5398.

Najoan, Jelly Juliana,. Max John R. Runtuwene dan Defny S. Wewengkang. 2016. Uji Fitokimia dan Aktivitas Antioksidan Ekstrak Etanol Daun Tiga (Allophylus cobbe L.). Pharmacon Jurnal Ilmiah Farmasi. Volume 5 (01). ISSN 2302-2493.

Lumowa, Sonja V. T dan Syahril Bardin. 2018. Uji Fitokimia Kulit Pisang Kepok (Musa paradisiaca L.) Bahan Alam sebagai Pestisida Nabati Berpotensi Menekan Serangan Hama Tanaman Umur Pendek. Jurnal Sains dan Kesehatan. Volume 1 (09). P-ISSN 2303-0267.

Misna, dan Khusnul Diana. 2016. Aktivitas Antibakteri Ekstrak Kulit Bawang Merah (Allium cepa L.) terhadap Bakteri Staphylococcus aureus. Galenika Journal of Pharmacy. Volume 2 (02). ISSN : 2442-8744.

Davis, W.W. and T.R Stout. 1971. Disc plate methods of microbiological antibiotic assay. J. Microbiology. (4):659-665.

Muwarni, dan Y Fatisa. 2011. Uji Efek Antimikroba Ekstrak Kulit Pohon Rambutan (Nephellium lappaceum L) Terhadap Escherichia coli Secara In Vitro. Laboratorium Mikrobiologi dan FAAL FKUB. Malang. Halaman 8.

Published
2018-12-31
How to Cite
Shabir, E. S., Rahmadani, A., Meylina, L., & Kuncoro, H. (2018). Uji Fitokimia Ekstrak Kulit Buah Salak (Salacca zalacca) dan Pengaruh Ekstrak terhadap Pertumbuhan Bakteri Streptococcus mutans dan Jamur Candida albicans. Proceeding of Mulawarman Pharmaceuticals Conferences, 8(1), 314-320. https://doi.org/10.25026/mpc.v8i1.346