Uji Aktivitas Antibakteri Ekstrak Daun Gelinggang (Cassia alata L)

Antibacterial Activity Test of Gelinggang Leaf Extracts (Cassia alata L)

Authors

  • Khofifah Nur Oktavia Laboratorium Penelitian dan Pengembangan Kefarmasian “Farmaka Tropis”, Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia
  • Fika Aryati Laboratorium Penelitian dan Pengembangan Kefarmasian “Farmaka Tropis”, Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia
  • Herman Herman Laboratorium Penelitian dan Pengembangan Kefarmasian “Farmaka Tropis”, Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

DOI:

https://doi.org/10.25026/mpc.v14i1.561

Keywords:

Gelinggang, Cassia alata, Antibacterial, Staphylococcus aureus, Escherichia coli

Abstract

Traditionally, gelinggang leaves are widely used for treatment of various skin diseases. The potential of gelinggang leaves as a medicinal plant is expected due to the presence of secondary metabolite compounds that have activities, one of which can inhibit the growth of fungi and bacteria. This study aims to determine the antibacterial activity of gelinggang leaf extract against Staphylococcus aureus and Escherichia coli bacteria. The study began with extraction process of gelinggang leaves, phytochemical screening tests and testing of antibacterial activity from gelinggang leaf extracts carried out by the agar diffusion method using a well. Gelinggang leaf samples were macerated with 96% ethanol solvent and then tested for antibacterial activity in concentrations of 5%, 10%, and 15%. The results of the phytochemical screening test indicated that the gelinggang leaf extract was positive for flavonoids, saponins, phenolics, and terpenoids. On antibacterial activity test of the ethanolic extract of gelinggang leaves, it revealed that there was an inhibition activity for both Staphylococcus aureus and Escherichia coli bacteria with the best activity at a concentration of 15%.

References

Fajri, M., Marfu’ah, N., Artanti, L O. 2018. Aktivitas Antifungi Daun Ketepeng Cina (Cassia alata L) Fraksi Etanol, N-Heksan, dan Kloroform Terhadap Jamur Micrisporium canis. Pharmasipha. 2 (1): 1-8

Arief, Hariana H. 2011. Tumbuhan Obat dan Khasiatnya Jilid 2. Jakarta: Penebar Swadaya

Nurlansi dan Jahidin. 2018. Uji Aktivitas Antibakteri Ekstrak Metanol Dan Fraksi Etilasetat Daun Ketepeng Cina (Casia Alata L). Indonesia Natural Research Pharmaceutical Journal Vol. 2, No. 2,

Triana, O., Fajar P., Hadi K., Laode R. 2016. Aktivitas Antijamur Ekstrak Daun Ketepeng Cina (Cassia alata L.). Jurnal Sains dan Kesehatan, Vol. 1 No. 6

Verdian, M., Widarta I W R., Permana, I D G M. 2018. Pengaruh jenis pelarut pada ekstraksi menggunakan gelombang ultrasonic terhadap aktivitas antioksidan ekstrak kulit buah lemon (Citrus limon (Linn.) burm F).Jurnal ilmu dan teknologi pangan. 7 (4): 213-222

Davis, W. W., Stout, T. R. 1971. Disc Plate Methods of Microbiology. 22(4): 659- 665

Nagappan, T P., Ramasamy, M E A., Wahid, T C, Segaran and Vairappan C S. 2011. Biological activity of carbazole alkaloids and essential oil of murraya koenigii against antibiotic resistant microbes and cancer cell lines. Molecules. 16: 9651-9664

Ibrahim, A., dan Kuncoro, H. 2012. Identifikasi metabolit sekunder dan aktivitas antibakteri ekstrak daun sungkai (peronema canescens Jack) terhadap beberapa bakteri pathogen. Journal of tropical pharmacy and chemistry, 2(1)

Madduluri, Suresh. Rao, K.Babu. Sitaram, B.2013. In Vitro Evaluation of Antibacterial Activity of Five Indegenous Plants Extract Against Five Bacterial Pathogens of Human. International Journal of Pharmacy and Pharmaceutical Sciences.2013:5(4): 679-684.

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Published

2021-12-31

How to Cite

Oktavia, K. N., Aryati, F., & Herman, H. (2021). Uji Aktivitas Antibakteri Ekstrak Daun Gelinggang (Cassia alata L): Antibacterial Activity Test of Gelinggang Leaf Extracts (Cassia alata L). Proceeding of Mulawarman Pharmaceuticals Conferences, 14(1), 160–165. https://doi.org/10.25026/mpc.v14i1.561

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