Kajian Efektivitas Pengobatan pada Pasien Stroke Iskemik di Instalasi Rawat Inap RSUD Nunukan

Study of Treatment Effectiveness in Ischemic Stroke Inpatients Instalation Nunukan Hospital

Authors

  • Rida Wahda Maulida Tahir Laboratorium Penelitian dan Pengembangan Kefarmasian “Farmaka Tropis”, Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia
  • Hifdzur Rashif Rija’i Laboratorium Penelitian dan Pengembangan Kefarmasian “Farmaka Tropis”, Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia
  • Niken Indriyanti Laboratorium Penelitian dan Pengembangan Kefarmasian “Farmaka Tropis”, Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

DOI:

https://doi.org/10.25026/mpc.v14i1.581

Keywords:

Ischemic Stroke, Drug Use, Drug Interactions

Abstract

Ischemic stroke occurs due to obstruction of the blood vessels that supply the brain. Obstruction occurs due to increased fat lining the blood vessels or atherosclerosis. Atherosclerosis will cause cerebral thrombosis and cerebral embolism. This study aims to examine effectiveness of the use of drugs in ischemic stroke patients hospitalization at Nunukan Hospital. This study is a non-experimental study with a descriptive analysis design using medical record data collected retrospectively and the number of samples in this study was 70 patients. The sample selection of this research was using purposive sampling technique. The results showed tthe highest characteristics of ischemic stroke patients by gender were male (54.29%), based on age group 45-65 years (64.29%), based on diagnoses with comorbidities (64.70%), and the length of treatment the most occurred in 5-10 days (72.55%). The most used drugs single therapy for ischemic stroke are antiplatelet drugs, namely aspirin (28.57%) and the most used combination therapy is piracetam and citicoline (50%). The most frequent drug interactions were aspirin and clopidogrel (48.57%). While the accuracy of drug use includes the right indication (100%), the right drug (94.29%), the right dose (97.14%), and the right frequency (97.14%). Thus, it was concluded that the treatment of ischemic stroke at the inpatient installation the Nunukan General Hospital was effective.

References

Wardhani Novida Rizky dan Santi Martini. 2014.Faktor yang Berhubungan Dengan Pengetahuan Tentang Stroke Pada Pekerja Institusi Pendidikan Tinggi. Jurnal Berkala Epidemiologi Vol.2 No.1

American Heart Association (AHA/ASA). 2019. Guidelines for the Early Management of PatientsWith Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke

Laily Siti Rohmatul.2017. Hubungan Karakteristik Penderita dan Hipertensi Dengan Kejadian Stroke Iskemik.Jurnal Berkala Epidemiologi Vol.5 No.1: 48-59. Surabaya:Universitas Airlangga

Riset Kesehatan Dasar (Riskesdas) (2018). Badan Penelitian dan Pengembangan Kesehatan Kementerian RI tahun 2018

Kemenkes.RI.2014. Pusdatin STROKE. Pusat Data Dan Informasi Kementrian Kesehatan.

Burhanuddin. M., Wahiduddin., Jumriani. 2013. Faktor Risiko Kejadian Stroke Pada Dewasa Awal (18-40 Tahun) di Kota Makassar Tahun 2010-2012. Jurnal MKMI

Nastiti. 2012. Gambaran Faktor Risiko Kejadian Stroke pada Pasien Stroke Rawat Inap di Rumah Sakit Krakatau Medika Tahun 2011. Jakarta: Universitas Indonesia

Watila, M.M., Nyandaiti, Y. W., Bwala, S. A., Ibrahim, A. 2010.”Gender Variation Risk Factor and Clinical Presentasion of Acute Stroke” Volume 3 (3), hal. 38-43.

Suiraoka. 2012. Penyakit Degeneratif. Yogyakarta: Nuha Medika

Junaidi. I. 2011.Stroke Waspadai Ancamannya. Yogyakarta:PT Bhuana Ilmu Populer Kelompok Gramedia

Fagan,S.C dan Hess, D.C. 2014.Stroke In: Dipiro Pharmacootheraphy: Patophysiologic Approach, 9th Edition. United State: Mc Graw Hill Companies

Patrono, C., et al. 2011. Antiplatelet agents for the treatment and prevention of atherothrombosis. European Heart Journal.

Kelompok Studi Stoke PERDOSSI. 2011. Guideline Stroke 2011. Jakarta: Perhimpunan Dokter Spesialis Saraf Indonesia (PERDOSSI).

Setiya, D., Didik, H., dan Nailis, S. 2013. Study Penggunaan Obat Neuroprotektan pada Pasien Stroke Iskemik .Pharmacy. 10 (2). Halaman 6.

Doijad,R.C., dkk. 2012. Therapeutic applications of citicoline and piracetam as fixed dose combination. Journal of Pharma and Bio Science Vol.2 (12).

Abraham, N.S., et al.2010. ACCF’ACG/AHA:2010 Expert Consensus Document on The Concomitant Use of Proton Pump Inhibitors and Thienopyridines: A Foccusd Update of The ACCF/ACG/AHA 2008 Expert Consensus Document on Reducing The Gastrointestinal Risk of Antiplatelet Therapy and NSAID Use.

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Published

2021-12-31

How to Cite

Tahir, R. W. M., Rija’i, H. R., & Indriyanti, N. (2021). Kajian Efektivitas Pengobatan pada Pasien Stroke Iskemik di Instalasi Rawat Inap RSUD Nunukan: Study of Treatment Effectiveness in Ischemic Stroke Inpatients Instalation Nunukan Hospital. Proceeding of Mulawarman Pharmaceuticals Conferences, 14(1), 254–261. https://doi.org/10.25026/mpc.v14i1.581

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